Places to see in San Francisco?

Yo. General enquiry here:

Female Parental Unit is going to be in San Francisco in two weeks, with a day or two free. She doesn't drive, though cabs are a possibility, and her interests mostly mirror mine apart from manga/anime. What's there for her to see, visit and/or shop at?

(And if anyone can point out good comic stores there, I would very much like to prepare a shopping list for her ^_^)

Also, I may possibly have a kitten. 300 km away, stripey, undertermined sex, apparently very cute. Lestat for a boy, Esme for a girl?